Abstract

The purpose of this systematic review is tounderstand the recent advances that have been madein understanding the risk factors and etiology behindthe rising incidence of precocious puberty in children.The key goals are to assess to understand the normalphysiology of the hypothalamic-pituitary-gonadal (HPG)axis and the various theories that have been proposedthat influence the normal functioning of the HPG axisleading to central precocious puberty

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