Abstract

Factors that increase the risk of CDI include malignancy, antibiotic usage, and increased number of comorbidities, chronic kidney disease, inflammatory bowel disease, cirrhosis, gastrointestinal surgery, proton pump inhibitors, histamine h2-receptor antagonists, and steroid use. Fortunately, affected by a decrease in health care associated infections, the incidence of CDI declined (154.9 to 143.6 per 100,000 persons) between 2011 and 2017.

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