Abstract

Some evidence suggests that early-life respiratory events might play a significant role in respiratory health throughout life. There have been retrospective classifications of wheezing phenotypes in childhood, such as (1) transient early wheezing, (2) late-onset wheezing, (3) persistent wheezing, and (4) never wheezed. In this prospective, population-based, birth cohort study in the United Kingdom, the parentally reported patterns of childhood wheezing obtained when the children were 3 and 5 years of age were compared with pulmonary function in these children as assessed by airways resistance measurements.

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