Abstract
The number of people living with dementia worldwide is estimated at 44 million, with projections indicating this number will double by 2030 and more than triple by 2050. 1 Alzheimer's Disease International: World alzheimer report 2014. London, 2014. Available at: http://www.alz.co.uk/research/world-report-2014 Google Scholar Neuropsychiatric symptoms (NPS) accompany cognitive decline almost universally, with 98% of patients experiencing NPS at some point in their illness. 2 Steinberg M. Shao H. Zandi P. et al. Point and 5-year period prevalence of neuropsychiatric symptoms in dementia: the Cache County Study. Int J Geriatr Psychiatry. 2008; 23: 170-177 Crossref PubMed Scopus (466) Google Scholar NPS are especially concerning because they are associated with more rapid disease progression, worse patient outcomes, excess morbidity and mortality, greater healthcare utilization, earlier nursing home placement, and increased caregiver burden. 3 Allegri R.F. Sarasola D. Serrano C.M. et al. Neuropsychiatric symptoms as a predictor of caregiver burden in Alzheimer's disease. Neuropsychiatr Dis Treat. 2006; 2: 105-110 PubMed Google Scholar , 4 Rabins P.V. Schwartz S. Black B.S. et al. Predictors of progression to severe Alzheimer's disease in an incidence sample. Alzheim Dement. 2013; 9: 204-207 Abstract Full Text Full Text PDF PubMed Scopus (50) Google Scholar Treatment of NPS may alter disease course, improve patient outcomes, decrease healthcare costs, and improve patient and caregiver quality of life.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
