Abstract
Background: Betahistine is an orally administered, centrally acting histamine H1 receptor agonist with partial H3 antagonistic activity and no H2–binding effects. In the past betahistine was clinically studied mainly as a vasodilator for conditions such as cluster headaches, vascular dementia and Meniere's disease, for which it is still used. In recent years, histamine was found to be a key neurotransmitter in the regulation of feeding behavior. Objective: To provide a review of the developmental history and current research interests of betahistine. Methods: All reports of betahistine use in animals and humans were retrieved and reviewed. Results/conclusion: The unique pharmacologic properties of betahistine point to its potential future use as an antiobesity agent.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
