Betablocker Use in Cerebral Proliferative Angiopathy: Case Report

Liem Glaucia Suzanna Jong A,Figueiredo Eberval Gadelha,Paschoal Eric Homero Albuquerque,Junior Fernando Mendes Paschoal,Teixeira Manoel Jacobsen,Bor-Seng-Shu Edson,Neto Feres Eduardo Aparecido Chaddad

doi:10.23937/2643-4474/1710097

Abstract

We describe a case of cerebral proliferative angiopathy in a patient with frequent episodes of disabling headaches. The clinical details, radiographic and angiogram findings and medical management are reviewed. This is the first described cerebral proliferative angiopathy case in which we noticed shrinkage of a vascular lesion with the use of a betablocker.

Highlights

A 29-year-old young man attended the neurosurgery outpatient clinic with a chief complaint of headache, mild cognitive impairment, and intermittent left upper limb paraesthesia
This study was complemented with a cerebral angioresonance where the vascular tangles were best described as a network of severe vascular ectasias with multiple small intracranial aneurysms sparse across the brain - compromising the basal ganglia, the basal cisterns, the polygon vessels, and the ventricular system - suggesting a complex arteriovenous malformation (AVM) or Moya-Moya disease
For a better elucidation of the case, the patient was submitted to an angiographic study where a vast vascular tangle was noted, interspersed with a functioning parenchyma with characteristics like those described by the neuroradiologist Lasjaunias, et al [1]

Summary

Introduction

A 29-year-old young man attended the neurosurgery outpatient clinic with a chief complaint of headache, mild cognitive impairment, and intermittent left upper limb paraesthesia. This study was complemented with a cerebral angioresonance where the vascular tangles were best described as a network of severe vascular ectasias with multiple small intracranial aneurysms sparse across the brain - compromising the basal ganglia, the basal cisterns, the polygon vessels, and the ventricular system - suggesting a complex arteriovenous malformation (AVM) or Moya-Moya disease. For a better elucidation of the case, the patient was submitted to an angiographic study where a vast vascular tangle was noted, interspersed with a functioning parenchyma with characteristics like those described by the neuroradiologist Lasjaunias, et al [1].

Results

Conclusion