'Beta version' of neuroplasticity or absolute beta power in preterm infants as electroencephalographic correlate of synaptogenesis

Abstract

Although numerous Schiff base complexes have been synthesized and characterized, reports on Schiff base ligands and complexes derived from amines containing terminal allyl group are rare. In this work, four halogenated Schiff base compounds were synthesized by reaction of halogenated salicylaldehydes (3,5-dichlorosalicylaldehyde, 3,5-dibromosalicylaldehyde, 3,5-diiodosalicylaldehyde and 3-bromo-5-chlorosalicylaldehyde) with allyl amine in water as green solvent at ambient temperature and characterized by elemental analyses, NMR (1H and 13C), and FT-IR spectroscopy. In continue, their Cu(II) complexes were synthesized and characterized by elemental analyses, FT-IR and single-crystal X-ray diffraction. All complexes show halogen-halogen, π–π, CH–π interactions and also metal–halogen secondary bonds in crystal packing. The coordination geometry around the Cu(II) in all reported compounds is best described as square planar with two axially elongated interactions named metal–halogen secondary bond (Cu…X), all beyond the sum of the corresponding vdW radii (3.421 Å for Cu…Cl in (Cl2L)2Cu, 3.463 Å for Cu…Br in (Br2L)2Cu, 3.486 Å for Cu…I in (I2L)2Cu and 3.467 Å for Cu…Cl in (BrClL)2Cu). The crystal structures have also been subjected to Hirshfeld surface analysis which reveals that approximately most of the close contacts correspond to relatively weak interactions. Also, all of the interactions in crystal packing have been analyzed by theoretical calculations.