Abstract
Type A aortic dissection (TAAD) is a catastrophic condition with 24–48% mortality during the first day, if patients are not surgically treated. Due to old age and associated co-morbidities surgeons may be reluctant to operate and patients are administered medical therapy for the end of reducing systolic blood pressure and heart rate. Beta-blockers (BB) are the “medications of choice”. Based on physical and physiological considerations, it was hypothesized that BB may actually exacerbate TAAD.
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