Berichtigung: Bioinspired, Size‐Tunable Self‐Assembly of Polymer—Lipid Bilayer Nanodiscs

Abstract

The University of Michigan found through its internal investigation1 that Sudheer Kumar Ramadugu, one of the co-authors on the paper, had falsified data in the spectra in Figures 4E and 4F in this Communication. The experiments have been repeated and the correct 14N NMR spectra (Fig. 4E and Fig. 1F) demonstrate the magnetic alignment of the macro-nanodiscs as originally reported. The 14N quadrupole couplings in Figure 4E and 4F have been corrected from 8 kHz and 16 kHz to 9 kHz and 18 kHz, respectively. 31P NMR spectra (Fig. 4B and 4C) for the new samples were also recorded. The chemical shift values have been corrected from −17.9 ppm to −13 ppm in Figure 4B and from 20 ppm to 22 ppm in Figure 4C. The corrected Figure 4 and associated caption are as follows. Magnetic-alignment of SMA-EA polymer based macro-nanodiscs: Static 31P (A–C) and 14N (D–F) NMR spectra demonstrate the presence of isotropic nanodiscs (ca. 10 nm diameter) (A,D), the magnetic-alignment of macro-nanodiscs (ca. 50 nm) with the lipid bilayer perpendicular to the external magnetic field (B,E), and flipped macro-nanodiscs (95:5 DMPC:DMPE-DTPA) in the presence of Yb3+ ions with the lipid bilayer parallel to the external magnetic field (C,F). G) 2D 15N–1H TROSY sQC spectrum of isotropic SMA-EA nanodiscs containing 15N-cytochrome b5 reconstituted in DMPC lipid bilayers. All spectra were recorded at 35 °C, where the DMPC lipids are in a fluid lamellar phase bilayer. H) 2D 1H–15N PISEMA spectrum of SMA-EA macro-nanodiscs containing 15N-cytochrome b5 reconstituted in DMPC lipid bilayers with the bilayer normal perpendicular to the external magnetic field. The new data have also resulted in a few minor changes to the text: On page 11626 the sentence should read: The observation of a peak at −13 ppm in the 31P NMR spectrum (Figure 4B) and approximately 9 kHz 14N quadrupole splitting (Figure 4E) suggest that the lipid bilayer normal is oriented perpendicular to the external magnetic field direction. On page 11627 the sentence should read: the 31P peak appeared at around 22 ppm (Figure 4C) and the 14N quadrupole coupling splitting increased by a factor of 2 to become about 18 kHz (Figure 4F). On page 11627 Figure 4I is no longer relevant and thus the sentence “The ability to control the extent of flip of macro-nanodiscs is also demonstrated by recording 31P spectra for various concentrations of Yb3+ (Figure 4I).” is no longer applicable. An updated Supporting Information for this paper is made available online along with this Corrigendum. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.