Abstract
The search for alternatives to combat antibiotics has been increased due to the upsurge in cases of antibiotic-resistant pathogens that has become a global phenomenon which threatens the human health. Medicinal plants provide multiple health benefits because these plants contain bioactive phytochemicals that are used in medicines as alternatives to various ailments of human beings. Bergenia ciliata is a perennial herb belongs to the family Saxifragaceae that consists of about 30 genera and 580 species worldwide. It has large, evergreen and leathery leaves with the pink to dark purple flowers and has various traditional and modern medical uses. This plant is considered is one of the most effective antibacterial agents. The present review emphasizes the antibacterial potential of Bergenia ciliata by compiling various researches and fragmented information. The most important phytochemicals derived from Bergenia ciliata launched on the pharmaceutical market are also discussed. This attempt will help the researchers to develop and synthesize new antibacterial drugs from Bergenia ciliata against drug-resistive pathogens.
Highlights
The interrelation of human beings with their surrounding herbs and medicinal plants draws its roots to the ancient civilizations [1]
In present study we have reviewed different extracts of Bergenia ciliata that can be used against pathogenic bacteria
It was published that rhizome extracts of Bergenia ciliata showed significant antibacterial potential against four bacterial strains; Klebsiella pneumonia, Staphylococcus auereus, Bacillus subtilis and Escherichia coli
Summary
The interrelation of human beings with their surrounding herbs and medicinal plants draws its roots to the ancient civilizations [1]. This review will help the researchers across the world to develop new antibacterial drugs from Bergenia ciliata against the resistive pathogens. There are about 58 phytochemicals present in Bergenia ciliata species of which 48 volatile organic compounds are categorized into 11 categories viz; alcohols, fatty acids, phenols, carboxylic acids, terpenoids, flavonoids, glycosides, nitro compounds, sterol, cinnamic acid and volatile organic compounds [10].
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