Abstract
Patients with ocular benign mucous membrane pemphigoid have had their conjunctival epithelium examined by means of pipette samples drawn from the conjunctival fluid for estimating the cell contents and smears from the conjunctiva.Of the 29 eyes examined, 24 showed metaplasia changing the columnar epithelium of a normal conjunctiva into squamous epithelium, with parakeratosis in 22 of these eyes. This result was achieved by analyzing three pipette samples and three smears from each eye. (Out of 88 pipette samples and 92 smears, 54 and 86, respectively, showed abnormal squamous epithelium and, in addition, 32 and 48, respectively, showed parakeratosis).Neutrophilia was noticed in a scant half of the pipette samples, an observation which bears out the hypothesis that the normal regeneration system has been destroyed in the presence of pemphigoid. The amounts secreted of both tears and mucus are reduced. The mucous thread in the inferior conjunctival fornix is rudimentary.
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