Abstract

Journal of Diagnostic Pathology is a peer reviewed journal published biannually by the College of Pathologists of Sri Lanka. The journal publishes manuscripts dealing with all aspects of pathology. The aim of the journal is to update knowledge and encourage original research in the field of pathology.

Highlights

  • This is seen in postmenopausal or in postnatal cervices that are devoid of oestrogen

  • This occurs in the transformation zone as a result of squamous metaplasia blocking gland outlets

  • They are lined by a flat single layer of mucin producing endocervical epithelium

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Summary

Benign mimics of cervical cancers S Manek

A vast number of benign lesions in the cervix are encountered in day to day practice. Many of these can mimic in situ and invasive neoplastic lesions and many precursor lesions and malignant neoplasms may mimic benign conditions. This is seen in postmenopausal or in postnatal cervices that are devoid of oestrogen. In the former, there can be considerable crowding of nuclei with some hyperchromasia and even disarray. They can mimic high grade cervical intraepithelial neoplasia (CIN) if one is considering attenuated CIN. Use of p16 and mib-1 immunohistochemistry usually helps to distinguish between the two

Deep Nabothian cysts
Tunnel clusters
Ectopic prostatic tissue
Reactive changes to inflammation
Decidual change
Papillary endocervicitis
Diathermy changes
Mesodermal stromal polyps
Placental site trophoblastic nodule
Mullerian papilloma
Papillary adenofibroma
Condyloma acuminatum
High grade CIN
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