Benign hyperglobulinemic purpura: case report.

Abstract

Case Reports1 February 1954BENIGN HYPERGLOBULINEMIC PURPURA: CASE REPORTFRANK E. TAYLOR, M.D., JOHN D. BATTLE JR., M.D., F.A.C.P.FRANK E. TAYLOR, M.D.Search for more papers by this author, JOHN D. BATTLE JR., M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-40-2-350 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe term hyperglobulinemic purpura was introduced by Waldenström1in 1943 to describe three patients with an unexplained increase in serum globulin, high sedimentation rate, and purpura of many years' duration. He recognized the benign nature of the condition and excluded the diagnosis of multiple myeloma, which shows several similar features. Since this initial observation, additional cases have been reported in the European literature (table 1). There have been no reports in American journals of similar cases. In this article we present a case report of a patient with hyperglobulinemic purpura who has been observed for 10 years; we also briefly...Bibliography1. Waldenström J: Clinical methods for determination of hyperproteinemia and their practical value for diagnosis; contributing to study of "essential high sedimentation reaction," Nord. med. 20: 2288, 1943. Google Scholar2. Curtz FR: Purpura hyperglobulinaemica, Ugesk. f. læger 108: 340, 1946. Google Scholar3. Humerfelt S: Purpura with hyperglobulinemia, Nord. med. 34: 1101, 1947. MedlineGoogle Scholar4. Lindeboom GA: Purpura hyperglobulinemica, Dermatologica 96: 337, 1948. CrossrefMedlineGoogle Scholar5. Oberste-Lehn H: Ein Fall von Purpura hyperglobulinaemica unter dem Bilde der Schambergschen Erkrankung, Zentralbl. f. Haut- u. Geschlechtskr. 7: 404, 1949-1950. Google Scholar6. Horster JA: Purpura hyperglobulinaemica (morphologische Besonderheiten und pathogenetische Untersuchungen), Acta Haematologica 4: 201, 1950. CrossrefMedlineGoogle Scholar7. Linke A: Primäre und sekundäre Dysproteinämie mit Purpura- und Raynaud-Syndrom, Arch. f. Dermat. u. Syph. 191: 123, 1950. Google Scholar8. Waldenström J: Zwei interessante Syndrome mit Hyperglobulinämie (Purpura hyperglobulinaemica und Macroglobulinämie), Schweiz. med. Wchnschr. 78: 927, 1948. MedlineGoogle Scholar9. Waldenström J: Three new cases of purpura hyperglobulinemica. A study in long lasting benign increase in serum globulin, Acta. med. Scandinav. Suppl. 226: 931, 1952. Google Scholar10. Bing J: Further investigations of hyperglobulinemia, occurrence and degree of hyperglobulinemia in various diseases. Ratio between hyperglobulinemia, hyperproteinemia and hypoalbuminemia (Formol gel-reaction), Acta med. Scandinav. 103: 547, 1940. CrossrefGoogle Scholar11. SchmenglerEsser FEH: Pathogenesis of purpura hyperglobulinaemica, Klin. Wchnschr. 30: 30, 1952. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication June 24, 1953.From the Department of Medicine, Cleveland Clinic, and The Frank E. Bunts Educational Institute, Cleveland, Ohio. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHypergammaglobulinemic purpura of WaldenströmPurpura hyperglobulinaemia in association with rheumatoid arthritis and ulcerative colitisLate Occurrence of Plasmocytoma of the Tongue in "Benign" Hyperglobulinemic Purpura of Waldenström Twenty-year Progress ReportROBERT P. SHEON, M.D., LENA A. LEWIS, PH.D., JOHN D. BATTLE JR., M.D., F.A.C.P.Sjögren's Syndrome with Benign Purpura HyperglobulinemiaPurpura Hyperglobulinemia of WaldenströmChronic lymphocytic leukemia associated with dysproteinemia and acquired hemolytic anemiaDie Elektrophorese in der DermatologieIdiopathic Benign Hyperglobulinemic PurpuraEssential cryoglobulinaemia 1 February 1954Volume 40, Issue 2Page: 350-356KeywordsGlobulinsMultiple myeloma Issue Published: 1 February 1954 PDF downloadLoading ...