Abstract
Bengt Westermark and our current understanding of tumor pathogenesis
Highlights
The field of cancer research has advanced so far over the past four decades—the precise time-span of Bengt Westermark’s career—that it would be unrecognizable to those who last visited it in 1972
We knew that cancer cells grew uncontrollably and that a number of carcinogens were likely to be genotoxic mutagens, i.e. that among their other functions they worked to induce cancer through their ability to damage the genes within human tissues
The flurry of activity searching for the retroviral agents causing human cancer failed, but it left a rich repository of information on genes that were associated with rapidly transforming retroviruses, and it was these genes, stolen from the genomes of normal cells, that opened up the field of molecular oncology, more precisely the research that revealed the molecular origins of human cancer
Summary
The field of cancer research has advanced so far over the past four decades—the precise time-span of Bengt Westermark’s career—that it would be unrecognizable to those who last visited it in 1972. Bengt Westermark and our current understanding of tumor pathogenesis We knew that cancer cells grew uncontrollably and that a number of carcinogens were likely to be genotoxic mutagens, i.e. that among their other functions they worked to induce cancer through their ability to damage the genes within human tissues.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
