BENEFITS OF OZONE THERAPY IN THE TREATMENT OF FOOT ULCERS IN PEOPLE WITH DIABETES MELLITUS

Francisco Walyson Batista,Thiago Araújo,Vanessa Aguiar Ponte,Maria Girlane Sousa Albuquerque Brandão

doi:10.30886/estima.v19.1090_in

Abstract

Objective: To identify the benefits of ozone therapy in the treatment of foot ulcers in people with diabetes mellitus. Method: Literature review carried out in the CINAHL, Cochrane Library, LILACS, PUBMED, SciELO, SCOPUS and Web of Science databases in the period between April and May 2020. In each database, the controlled descriptors were delimited in the Science Descriptors of Health and Medical Subject Headings, keywords defined: Ozone (Ozone), Diabetic Foot (Diabetic foot), with the help of the Boolean operator AND. Results: 14 primary studies were selected. Most studies have level II evidence, published in English, in different journals, from different parts of the world. 15 benefits of ozone therapy for the treatment of foot ulcers were identified, with a predominance of increased granulation tissue and intensification in the progress of tissue repair. Conclusion: The use of ozone therapy has shown several benefits in the progress in tissue repair of foot ulcers in people with diabetes, increased granulation tissue, promoted antiseptic and bactericidal activities, preventing oxidative stress.

Highlights

Ozone therapy is a therapeutic resource that uses the ozone molecule as its main component, and its application can be combined with oxygen in different concentrations
This study aims to identify the benefits of ozone therapy in the treatment of foot ulcers in people with diabetes mellitus (DM)
A study in Iran identified as a benefit of ozone therapy the reduction in sedimentation of erythrocytes, c-reactive protein and reduced fasting blood glucose[8].This data demonstrates that the therapy under study can provide the patient with secondary outcomes that help in conducting foot ulcer healing

Summary

Introduction

Ozone therapy is a therapeutic resource that uses the ozone molecule as its main component, and its application can be combined with oxygen in different concentrations. Manipulated since World War II, ozone has been touted as an adjuvant therapy for wound care[1]. This therapy is regulated by health surveillance agencies in several countries, such as Germany, China, Cuba, Spain, Greece, Portugal, Russia and Turkey[2]. In Brazil, ozone therapy is regulated by a Bill of the Federal Senate (227/2017), which authorizes the prescription of ozone therapy as a complementary treatment within the Unified Health System (Sistema Único de Saúde-SUS3). Technology can be applied to improve outcomes to treat injuries of different etiologies, raising the quality of care for patients affected with skin lesions[4]

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Discussion

Conclusion