Abstract

Chronic kidney disease (CKD) is a disease that causes a decrease in kidney function, which can be seen from GFR (Glomerulus Filtration Rate) value, which is less than 60 ml/minute/1.73 m2 in minimum three months. Depression is a psychological problem in a patient with chronic kidney disease undergoing hemodialysis. The previous study has shown that giving vitamin B combination can improve depression symptoms. To measure the benefit of vitamin B1, B6, B12 parenterally for depression symptoms in chronic kidney disease patients undergoing hemodialysis. This study used an experimental design (one group pre and post-test) in 117 patient that obtained using a consecutive sampling method. Depression score was measured by the HADS questionnaire before given vitamin B (pre-test) and after given vitamin B (post-test). Data were statistically analyzed using a licensed SPSS program with paired t-test/Non-Parametric Wilcoxon. The relationship between the history of the use of the antihypertensive, antidiabetic, folic acid drug, and depression scores were not showing significant results (p > 0.05). The relationship between administration of vitamins B1, B6, and B12 and the patient's depression score showed a decrease but not significant (p = 0.522). There was no significant difference after the administration of vitamin B1, B6, and B12 on the depression score of patients with chronic kidney disease undergoing hemodialysis at Bethesda and Panti Rapih Hospital in Yogyakarta.

Highlights

  • Chronic Kidney Disease (CKD) is a disease that a big problem in the world

  • Visit I is the first week of taking depression score data before treatment, which is a parenteral combination of vitamin B in patients with chronic renal failure undergoing hemodialysis

  • This study concludes that there is a decrease in the mean depression score from before giving vitamin B and after giving vitamin B, but the analysis is not significantly different

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Summary

Introduction

Chronic Kidney Disease (CKD) is a disease that a big problem in the world. Chronic Kidney Failure is defined as a decrease in kidney function, which can be seen from the value of the GFR (Glomerulus Filtration Rate)Which is below the average value, which is less than 60Open Access ml/min/1,73 m2 in at least three months. Chronic Kidney Disease (CKD) is a disease that a big problem in the world. Chronic Kidney Failure is defined as a decrease in kidney function, which can be seen from the value of the GFR (Glomerulus Filtration Rate). The global average prevalence of chronic kidney disease reaches 13.4% (Hill et al, 2016). Indonesia is a country with a high rate of kidney failure patients. It is estimated that there are around 12.5 % of the population, or as many as 25 million Indonesians have decreased kidney function (Perkumpulan Nefrologi Indonesia, 2014). Yogyakarta is among the top five highest prevalence in Indonesia, with a CKD prevalence of 0.3%. The highest prevalence in Yogyakarta is found in Gunung Kidul and Yogyakarta City, which is 0.5% (Kementerian Kesehatan Republik Indonesia, 2013)

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