Abstract
BackgroundResults of previous studies have shown that exercise training can improve cognitive functions in healthy older people. Some studies have demonstrated that long-term combination exercise training can facilitate memory function improvement better than either aerobic or strength exercise training alone. Nevertheless, it remains unclear whether short-term combination exercise training can improve diverse cognitive functions in healthy older people or not. We investigate the effects of four weeks of short-term combination exercise training on various cognitive functions (executive functions, episodic memory, short-term memory, working memory, attention, reading ability, and processing speed) of healthy older people.MethodsA single-blinded intervention with two parallel groups (combination exercise training; waiting list control) is used. Testers are blind to the study hypothesis and the participants’ group membership. Through an advertisement in a local newspaper, 64 healthy older adults are recruited and then assigned randomly to a combination exercise training group or a waiting list control group. Participants in the combination exercise training group must participate in the short-term combination exercise training (aerobic and strength exercise training) three days per week during the four weeks (12 workouts in total). The waiting list group does not participate in the combination exercise training. The primary outcome measure is the Stroop test score: a measure of executive function. Secondary outcome measures are assessments including the Verbal Fluency Task, Logical Memory, First and Second Names, Digit Span Forward, Digit span backward, Japanese Reading Test, Digit Cancellation Task, Digit Symbol Coding, and Symbol Search. We assess these outcome measures before and after the intervention.DiscussionThis report is the first of a study that investigates the beneficial effects of short-term combination exercise training on diverse cognitive functions of older people. Our study is expected to provide sufficient evidence of short-term combination exercise’s effectiveness.Trial registrationThis trial was registered in The University Hospital Medical Information Network Clinical Trials Registry (Number UMIN000007828).
Highlights
Results of previous studies have shown that exercise training can improve cognitive functions in healthy older people
The results showed that the combination exercise training group, which performed walking and strength exercise training, exhibited more significant improvement than a control group, which received educational classes, in the Alzheimer Disease Assessment Scale (ADAS) and word recall tests
Randomized controlled trial design and setting of this trial This study, which was registered in the University Hospital Medical Information Network (UMIN) Clinical Trial Registry (UMIN000007828), is an randomized controlled trials (RCT) conducted in Sendai city, Miyagi prefecture, Japan
Summary
A single-blinded intervention with two parallel groups (combination exercise training; waiting list control) is used. Through an advertisement in a local newspaper, 64 healthy older adults are recruited and assigned randomly to a combination exercise training group or a waiting list control group. The waiting list group does not participate in the combination exercise training. Secondary outcome measures are assessments including the Verbal Fluency Task, Logical Memory, First and Second Names, Digit Span Forward, Digit span backward, Japanese Reading Test, Digit Cancellation Task, Digit Symbol Coding, and Symbol Search. We assess these outcome measures before and after the intervention
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