Abstract

The pivotal role of childhood nutrition has always roused a growing interest from the scientific community. Plant extracts and bioactive dietary components play a significant role in the maintenance of human health and wellness, with the potential to modulate risk factors and manage symptoms for a large number of common childhood disorders such as memory impairment, respiratory illnesses, gastrointestinal disorders, metabolic derangements, and pathologies related to the oral cavity. This review is designed to highlight the health benefits of botanical extracts and bioactive dietary components in children as evidenced by clinical trials, considering their safety with regards to childhood sensibilities. The supplementation of children with the herbal extracts or bioactive components mentioned in this review leads to the conclusion that they are useful for treating various ailments, with no serious adverse events being reported. However, for the limited number of investigations specifically focused on the safety of such products in children, time is needed to expand the literature data covering the safety of childhood supplementation with botanical extract and bioactive food components.

Highlights

  • The use of dietary supplements worldwide has increased in the last 30 years [1].Dietary supplements are used in the age group ranging from birth to 18 years of age, by31% of the population, to improve overall health (41%), maintain health (37%), supplement the diet (23%), prevent health problems (20%), and “boost immunity” (14%) [2]

  • Plant extracts are used for children, their use must be regulated by the awareness that children differ from adults in terms of physical size, body composition, and physiology

  • Sixty-four subjects finished the protocol, and the analysis of the results revealed a significant decrease in the median duration of diarrhea, vomiting, and fewer in the probiotic treatment group when compared with the placebo, while no effect on the duration of hospitalization was seen

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Summary

Introduction

The use of dietary supplements worldwide has increased in the last 30 years [1]. 31% of the population, to improve overall health (41%), maintain health (37%), supplement the diet (23%), prevent health problems (20%), and “boost immunity” (14%) [2]. From data by the World Health Organization (WHO), around 80% of the adult population in developing countries uses plant extracts for their health needs [3,4,5]. Plant extracts are used for children, their use must be regulated by the awareness that children differ from adults in terms of physical size, body composition, and physiology. In a German study, 85% of children used one or more herbal supplement products [5]. Another study reported that 16% of Japanese pediatric surgical patients use herbal supplement products [7]

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