Abstract

Background and Aims : Chronic kidney disease (CKD) patients present increased cardiovascular (CV) morbidity and mortality, with atherosclerosis being the underlying phenomenon in most of CV events. Clinical trials and metanalyses have linked administration of pentoxifylline (PTX) with renoprotection secondary to anti-inflammatory and antifibrotic effects in CKD patients, together with increased levels of the anti-aging protein Klotho. However, the effect of PTX on atherosclerosis in CKD patients has not been analysed.

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