Abstract
BackgroundsAlthough the physical and mental enhancement effect of essential oils have been proved, the beneficial effect of essential oil in central fatigue remains unclear. In this study, we extracted essential oils from nine aromatic plants to make a compound essential oil, and detected the therapeutic effect of central fatigue by daily aerial diffusion.MethodsThirty-three rats were randomly and equally divided into control group, chronic sleep deprivation group, and compound essential oil inhalation group. Central fatigue was generated by chronic sleep deprivation.ResultsAfter 21-day various interferences, it is found that the sleep deprivation rats showed an evident decrease in physical endurance, negative emotion, and cognitive dysfunction compared with the control group, and the group that treated with the compound essential oil behaved significantly better than central fatigue group.ConclusionWe concluded that this formula of essential oils could alleviate central fatigue on rats, and our study provides a new direction of application of aromatic therapy, which could be expanded to insomnia, depression and other healthy issue in the further research.
Highlights
A lot of clinical evidence has proved that aromatherapy could improve the brain function and alleviate fatigue [1]
Thirty three rats were randomly divided into three groups as follows: control group (CON, rats were fed routinely for 21 days, n = 11), chronic sleep deprivation group (CSD, rats were promoted by chronic sleep deprived for 21 days, n = 11), compound essential oil group (CEO, rats were promoted with chronic sleep deprived for 21 days with compound essential oil inhalation every day, n = 11)
The bodyweight of Chronic sleep deprivation group (CSD) group showed a significant decrease compared with Control group (CON) group (p = 0.000)
Summary
A lot of clinical evidence has proved that aromatherapy could improve the brain function and alleviate fatigue [1]. Clinical manifestation related to central fatigue reported in current literatures mainly including fatigue sensation, Han et al BMC Complementary and Alternative Medicine (2018) 18:309 weakness of physical function, low efficiency during mental task, and negative emotions including anxiety, depression [11]. It is a complex state which could be induced by massive physical and/or mental tasks [12]. Relax therapy [15] and sufficient oxygen [16] could improve the situation, an effective and suitable medical intervention for central fatigue remains absent
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