Abstract
Objective To explore the protective method of residual renal function in patients with stage Ⅲ type 2 diabetic nephropathy.Methods 70 patients with stage Ⅲ type 2 diabetic nephropathy were randomly divided into study group ( 38 patients ) and control group ( 32 patients ).The study group received benazepril combining with Chinese therapy with Yishen Gujing Huoxue,and the control group received benazepril alone.Results There was a significant difference in cystatin C levels between pre-treatment and post-treatment in the study group [( 1.62 ± 0.59 )mg/L vs.( 1.29 ± 0.38 ) mg/L,t =2.899,and P=0.005] and cystatin C levels differed significantly between the study group and the control group after treatment [( 1.29 ± 0.38 ) mg/L vs.( 1.51 ± 0.43 ) mg/L,t =2.272,and P=0.026].The renal survival curve did not cross between the two groups.The study group was superior to the control group in renal survival rate (92.1％vs.75％, Log-rank test:x2=4.227, P=0.040).Conclusions Benazepril combining with Chinese therapy with Yishen Gujing Huoxue may play a better role in the protection of residual renal function in patients with stage Ⅲ type 2 diabetic nephropathy. Key words: Diabetic nephropathy; Residual renal function; Therapy with traditional Chinese and Western medicine
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