Abstract

ABSTRACTThis is a study of leucocyte inhibitory factor (LIF) in patients with Behçet's disease using an extract from a reactive (pathergic) lesion as an antigen and, as a control, an extract from normal skin of a normal subject. The purpose is to search for the possible existence of an antigen in the skin that may explain the development of this reactive lesion following a trivial trauma.The LIF was tested in 9 patients with the disease; in 7 both during remission and exacerbation of symptoms, and in 9 healthy matched controls. The results failed to indicate any existence of an antigen in the skin of the tested patients.

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