Abstract
1. Lethal-no-imaginal-bud larvae become phenotypically normal if early third instar lymph glands or imaginal buds are transplanted into them before they develop the lethal phenotype. Both tissues were thrown down as melanised black bodies at the end of the third instar. 2. It was argued that the lymph gland transplant has inhibited the development of cell hypertrophy through its secretion, while the imaginal bud transplant seems to have stimulated the production of corresponding antibodies. The imaginal buds are thought to behave as isoantigens in the bud-free haemolymph ofl-nib larvae. 3. Early third instar wild type buds, or even saline solution, caused the melanisation of the cells of the lymph glands if injected into early third instar wild type larvae.
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