Abstract
The microfluidic devices have a wide applications on cell sorting and separation in recent years, and they could be a powerful tool to study the motion, deformation and adhesion of blood cells. On the other hand, the studies on the behaviors of blood cells in microfluidics could also help to design and optimize the microfluidic devices for cell sorting and separation. In this work, we firstly introduce the mechanism of cell deformation and adhesion generated in the flow in microchannels, emphatically for red blood cells. Then, we focus on the typical microfluidic devices and their functions on cell sorting and separation based on the cells’ behaviors of deformation and adhesion.
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