Abstract
This study investigated the concept of behavioral phenotypes by comparing behavior ratings of 91 children with Down syndrome, 28 children with Prader-Willi syndrome, 68 children with Angelman syndrome, and 24 children with nonspecific mental retardation. Results supported distinctive behavioral profiles for the syndrome groups. The Down syndrome group showed good social skills and low ratings of problem behaviors including hyperactivity. Children with Prader-Willi syndrome exhibited a pattern of externalizing, obsessive–compulsive, anxious, and overly sensitive behaviors. A profile of a happy disposition, hand clapping, mouthing behaviors, and severe levels of hyperactivity and attention problems emerged for children with Angelman syndrome. Implications for clinical practice and future research were discussed.
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