Abstract

This work is devoted to a comparative study of pharmacokinetic properties of complex compounds labeled with gallium-68 aminoglucose (68Ga-NODA-AG) or thioglucose (68Ga-NODA-TG) in BALB/c mice after intravenous administration. Statistical significance of activity accumulation in most organs and tissues was observed only at 5 min post-injection. At the following terms, these values didn’t have any statistical significance in most organs and tissues. Activity was eliminated from organs and tissues with high rate. The biological and effective half-lives of 68Ga-NODA-AG and 68Ga-NODA-TG from organs and tissues were less than 1 hour.

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