Abstract

Twelve monkeys ( Macaca mulatta) were recovered after arrest of cerebral blood flow lasting for periods of 4–14 min. Only the animal arrested for 14 min showed evidence of gross neurologic deficits 24 hr postsurgically. These animals were then run through a battery of tests to determine the existence of any residual behavioral deficits. Two of 12 animals showed clear evidence of brain damage (arrest periods of 10, and 14 min). The remaining animals representing arrest periods of 4–13 min showed no evidence of deficit. Where evidence of possible or definite brain damage occurred, the degree of deficit was positively related to the duration of arrest of cerebral blood flow.

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