Abstract
Rats were exposed to a CER procedure in which sucrose drinking was suppressed by a tone previously paired with shock. Suppression of drinking during the tone was reduced by mescaline (50 mg/kg) independently of whether training took place under mescaline or placebo. Additional data on the effect of mescaline on sucrose drinking indicated that the result could not be attributed to an increased drive to drink sucrose. It was proposed that mescaline releases behavior from inhibitory control. A number of studies from the literature were cited which supported this hypothesis.
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