Behavioral and ERP indices of self-schematic processing show differential associations with emerging symptoms of depression and social anxiety in late childhood: Evidence from a community-dwelling sample

Abstract

Symptoms of depression and social anxiety elevate in late childhood. An identified cognitive risk to both depression and social anxiety is maladaptive self-schemas (or self-schematic processing). Beyond the behavioral indices of this construct, event-related potentials (ERPs) during self-schematic processing have also been observed to be associated with depression or depressive symptoms. However, no study has examined the ERPs underlying self-schematic processing in relation to social anxiety. More importantly, it was unclear to what extent behavioral and ERP indices of self-schematic processing were differentially associated with depression and social anxiety, especially in typical-risk youth with emerging symptoms. A hundred and fifteen community-dwelling children (66 girls; Mean age=10.91 years, SD=1.45) completed a self-referent encoding task (SRET) with EEG recorded. A Principal Component Analysis identified a late positive potential (LPP) component elicited in both the positive and negative SRET conditions. Multivariate multiple regression showed that in both conditions, behavioral SRET scores were associated with depressive symptoms while partialling out social anxiety symptoms, but not with social anxiety symptoms with depressive symptoms partialled out. The LPP amplitude elicited in both conditions showed marginally positive associations with social anxiety symptoms while partialling out depressive symptoms, but not with depressive symptoms while accounting for social anxiety. This study provides novel evidence concerning the ERP correlates of self-schematic processing in relation to social anxiety symptoms. More importantly, our findings for the first time speak to the differential associations between the behavioral SRET scores and SRET-elicited LPP and emerging symptoms of depression and social anxiety in late childhood.