Abstract

Considerable evidence is accumulating which demonstrates a relationship between immune function and behavioral states such as object loss or depression. Findings have been described using animal and clinical models, and a complex chain of biological and psychological processes may be involved. Further research on behavioral, central nervous system, and immune interactions in childhood is needed and is especially important since the developing immune system may be particularly susceptible to behavioral effects. Effects on the immune system in early life may have profound long-term effects on immune capacity.

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