Abstract
Obesity is considered a disease of the century and several treatment methods have been researched. Traditional Chinese medicine describes several findings that can be used to treat this disease. Thus, the aim of the present study was to evaluate, from an experimental perspective of Western medicine, the biochemical and behavioral effects of pharmacopuncture (21 and 40) in obese Wistar rats. The HDP21 group, treated with pharmacopuncture, exhibited a reduction in body weight compared to controls, who were also fed a high-calorie diet. In the eating behavior test, the latency was lower in the HDP40 group, and in this group, animals consumed with a higher number of cereals compared to other obese groups, or with suggestions of high acupuncture or appetite in this group. The HDP21 group, on the other hand, exhibited the shortest time in closed arms when compared to the other groups, suggesting a reduction in anxiety. Regarding the perirenal fat weight and abdominal postmortem of groups fed a high calorie diet, the HDP21 group had the lowest weight of perirenal fat and abdominal fat compared to the others. Similarly, a reduction in cholesterol, triglyceride and glucose levels was observed in the HDP21 group compared to other groups that received a high calorie diet. In conclusion, the present study demonstrated the effectiveness of the pharmacopuncture that uses bee venom in ST21 with weight loss in obese rats, as well as the reduction in biochemical tests and with loss of anxiety.
Highlights
Acupuncture has been reported as a weight loss treatment for obese patients
There are several hurdles in the treatment of obesity; a disease that has been continuously growing in the modern world
Acupuncture is a treatment that is being used as a complementary therapy for obesity [3] and is recognized by the WHO
Summary
Acupuncture has been reported as a weight loss treatment for obese patients. The use of pharmacopuncture focusing on behavioral analyses has not yet been studied with the objective of treating obesity. This study aimed to assess the biochemical and behavioral effects of using pharmacopuncture techniques in obese Wistar rats. Obesity and overweight are directly linked to the development of a series of chronic disease conditions. Socioeconomic level and schooling are risk factors of overweight and obesity [25]. The sustained weight loss of 3 to 5 % results in clinically significant reductions in triglycerides, glycemia, and glycated hemoglobin levels, as well as a lowered risk of developing type 2 diabetes [7]
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