Abstract
The behaviour of the perchlorsoluble mucoproteic fraction from plasma, from neoplastic tissue and from peritumoral connective neoplastic tissue has been studied in rats hearing experimental cancers (Galliera sarcoma, 3,4-benzpyrene tumour, Warker adenocarcinoma). The mucoproteic content of the neoplastic tissue was observed to be constant during the tumour growth; on the contrary the level of the same fraction from peritumoral connective tissue gradually increases till a rather advanced stage of the tumour growth, after which the increase is no more evident. The hypothesis is advanced that such local process may be responsible (at least partially) for the increase of the circulating perclor-soluble protein which is also observed to be gradually and markedly increased during the growth of the grafted malignant tissue.
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