Abstract
The behavior of isolated nuclei of testicular and cauda and caput epididymal spermatozoa of the hamster injected into mature unfertilized hamster eggs was studied. Decondensation of nuclei within the egg cytoplasm was observed regardless of the type of spermatozoa used and whether the eggs were activated or not. In activated eggs the decondensed nuclei of testicular and cauda but not caput epididymal spermatozoa transformed into pronuclei. This failure of caput epididymal spermatozoa nuclei to transform into pronuclei may be due to a factor in the nuclei which prevents such a transformation. It is possible that this factor may be inactive or absent in the nuclei of testicular spermatozoa or may be inactivated by another factor while spermatozoa are present in the cauda epididymis.
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