Abstract
I am humbled and immensely honored to be awarded the 2020 William and Christine Hartmann Prize in Auditory Neuroscience. This talk will be composed of three stories, designed to honor the dedicated people who have shared my enthusiasm for trying to more fully understand development of the ear, the brain and hearing during the past half century. Story 1 will trace some of the questions we’ve pursued and why; from fundamental studies on behavior and brain development in neonatal chickens, to development of cochlear frequency maps, to hair cell death and regeneration and to understanding new details of binaural processing. Story 2 will discuss the rationale and some of the results underlying the 40 + years of studies on the biological interactions between the ear and the brain during development; interactions whereby activity shapes the structural and functional architecture of auditory pathways in the brain. Finally, Story 3 will describe our foray into the world of translational pharmacology, developing a new model to more fully understand hair cell death and using it to discover a new drug that may prevent hearing and balance disorders due to ototoxic medicines.
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