Abstract
Development of the vulva of the nematode Caenorhabditis elegans is a model for studying cell fate signaling. The epidermal growth factor receptor-like tyrosine kinase (LET-23) stimulating a Ras-mitogen-activated protein kinase pathway, as well as the Notch-like pathway and the Wnt pathway, contribute to vulval development. A gain-of-function mutant of the Gαq homolog, EGL-30, exhibited rare ectopic vulval tissue. These worms also exhibit hyperactive locomotor and egg-laying behaviors.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
