Abstract

The C400IONS system is the first multi-ion particle therapy system based on a cyclotron world-wide. The first treatment delivery is foreseen in Caen, France in 2026. This work provides major beam delivery and patient alignment specifications and design evaluations that will be integrated in the first installation. The C400IONS is an innovative system developed on a 400 MeV/u isochronous cyclotron, it can generate carbon ions, protons and helium ions. The beam delivery and treatment room design of this multi-ion treatment system is based on the IBA Proteus®PLUS equipment. The C400IONS fixed horizontal beamlines use pencil beam scanning technology and provide, e.g., planar imaging, a 6D robotic patient positioning system coupled with either a couch or a chair, and options to use patient or treatment specific accessories like a ripple filter. Nozzle and chair have been designed for optimal clinical perspectives for adult and pediatric treatments. The Beam Delivery System will provide scan fields from 20 × 20cm2 for carbon ions up to 30 × 30cm2 for protons. Beams will be available for treatment with ranges between 4 and 32 g/cm2 for protons and helium ions and between 4 and 27 g/cm2 for carbon ions. The nozzle shape and bottom clearance have been optimized for a chair designed for brain and head and neck treatment with several backrest heights and rotation settings enabling a large treatment volume. This work describes design investigations by Nha and its partners on nozzle and patient positioning components, supporting a reliable, comprehensive, optimized and evolutive multi-ion therapy system.

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