Abstract

The shocking discovery that the majority (75%–89%) of preclinical research studies, predominantly oncology related and published in top-tier journals, could not be reproduced was recently reported for 2 independent retrospective observational studies (1, 2). The findings of nonreproducibility in these studies were interestingly consistent. What can help determine whether research results will stand the test of time? In a recent article in Nature , Begley noted that whether you are an author, …

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