Abstract

2021 marks the centenary of the bacillus Calmette-Guérin (BCG) vaccine. In our review ‘100 Years of BCG Immunotherapy: From Cattle to COVID-19’, we highlight key milestones in the history of BCG, beginning from its discovery by Alfred Calmette and Camille Guérin to its present day use in tuberculosis (TB) prevention and as intravesical therapy for non-muscle-invasive bladder cancer.

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