Abstract
Aim: Renal replacement therapies (RRT), including dialysis modalities and renal transplantation (RT), affect patients’ quality of life (QoL) differently. This study aimed to determine the factors affecting the QoL in hemodialysis (HD) and RT patients.
 Material and Method: One hundred patients in each RT and HD group were included in the study. Socio-demographic data was determined with a questionnaire. Laboratory information and other medical information of the patients were obtained from the medical records. Short Form-36 (SF-36) and Nottingham Health Profile (NHP) scales were used to assess the QoL.
 Results: The mean ages in HD and RT patients were 58.28±15.21 and 47.92±12.01 years. Most patients were male (53% HD, 68% RT). RT patients had a higher QoL than HD patients in all components. On the NHP scale, RT patients had higher QoL in all parts except social isolation and emotional reactions. Male gender, non-smoker status, high education level, being employed and living in the city, and some laboratory parameters (hemoglobin, ferritin, sodium, calcium, magnesium, and albumin) positively affected the QoL in the HD group; diabetes and CVD had a negative impact on the QoL. In the RT group, male gender, high education level, being employed; normal potassium, phosphorus, and parathormone levels affect QoL positively while hypertension and CVD negatively affect the QoL.
 Conclusion: Factors affecting QoL in patients receiving RRT are different. Efforts to correct laboratory parameters may impact the quality of life in HD patients. Returning to working life could increase the QoL in RT patients.
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