Abstract
Partial table of contents: MAJOR ISSUES Ethically Optimizing Clinical Trials (K. Schaffner) Admissibility of Treatment (N. Sedransk) TEST CASE: VERAPAMIL/NITROPRUSSIDE The Mechanics of Conducting a Clinical Trial (E. Heitmiller & T. Blanck) Issues of Statistical Design (N. Sedransk) Operational History and Procedural Feasibility (J. Kadane) Verapamil versus Nitroprusside: Results of the Clinical Trial I (J. Kadane & N. Sedransk) Verapamil versus Nitroprusside: Results of the Clinical Trial II (E. Heitmiller, et al.) OTHER ISSUES Author's Response to Commentaries I and II (D. Kairys) EPILOGUE Epilogue (J. Kadane) Indexes.
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