Abstract
Cancer is characterized by abnormal gene function and aberrant patterns of gene expression. A growing body of data suggests that acquired epigenetic aberrations work in concert with genetic changes to generate this deregulation. According to a WHO research, India saw 1.16 million new cancer cases in 2018, with one out of every ten Indians developing cancer at some point in their life and one out of every 15 dying from it. According to the study, tobacco-related head and neck cancers are frequent in India, especially oral cancer in males and cervical cancer in women, and both cancer types are linked to lower socioeconomic position. Conclusion: Tobacco use is becoming a leading cause of cancer in the North East, and it is estimated that tobacco use is responsible for 22% of cancer deaths worldwide. A comprehensive cancer control program is the need of the hour to prevent this vibrant region from becoming the cancer capital of the nation.
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