Abstract

In order to determine the safety of the use of amantadine in intensive treatment of victims with severe traumatic brain injury, a prospective controlled blind randomized study was conducted, in which 31 patient were included. The first group consisted of 19 persons who underwent intensive treatment. In group II (18 people), amantadine was included in the intensive care package. The use of amantadine in the complex intensive treatment of severe traumatic brain injury at the earliest possible time (3rd day after injury), provided the correction of hemodynamics and respiration does not change the structure and does not exacerbate the manifestations of polyorgan insufficiency.

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