Abstract

At the Gonda Neuroscience and Genetics Research Center at UCLA, there is a cafeteria called “The Synapse.” In addition to invoking a meeting place for people encouraging the free exchange of ideas between distinct scientific disciplines, the name of the cafe also refers to the major structure for exchange of information between neurons (the neuronal synapse) and chromosomes (the meiotic chromosomal synapse). In a similar fashion, the last decade has witnessed a dramatic exchange of information between the basic brain science and genetics that is shining a clearer light on the molecular mechanisms of the psychiatric disorders affecting elderly patients and giving new entry-points for future therapies.

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