Abstract
Background: The Japan Environment and Children’s Study (JECS) is a nationwide birth cohort study of environmental factors affecting children’s health and development. We summarize the complete blood count and chemistry panel statistical data from pregnant women enrolled in JECS. Methods: Statistical data of up to 58,056 mother’s sample in their first (gestational age ≤ 13 weeks) and second trimester (22–27 weeks) were calculated. Results: Mean (SD) values in the first trimester were: white blood cell count, 7866 (1906)/μL; red blood cell count, 417 (33) 104/μL; hemoglobin, 12.4 (1.0) g/dL; hematocrit, 37.1 (2.6)%; mean corpuscular volume, 89.2 (4.7) fL; mean corpuscular hemoglobin, 29.8 (1.9) pg; mean corpuscular hemoglobin concentration, 33.3 (0.9)%; platelet count, 24.8 (5.2) 104/μL; HbA1c, 5.26 (0.26)%; total cholesterol, 181 (28) mg/dL; low density lipoprotein cholesterol, 95 (23) mg/dL; high density lipoprotein cholesterol, 73 (13) mg/dL; free cholesterol, 41 (7) mg/dL; triglycerides, 109 (47) mg/dL; total protein, 6.9 (0.4) g/dL; and albumin, 4.1 (0.2) g/dL. Mean values (SD) in the second trimester were: total cholesterol, 246 (38) mg/dL; free cholesterol, 61 (9) mg/dL; triglycerides, 183 (70) mg/dL; total protein, 6.5 (0.4) g/dL; and albumin, 3.6 (0.2) g/dL. Conclusions: These data will be useful for future JECS studies.
Highlights
The Japan Environment and Children’s Study (JECS) is a nationwide birth cohort study launched in January 2011 to evaluate the effects of chemical exposure during the fetal stage and in early childhood on children’s health and development [1]
We confirmed a wide range of maternal baseline demographic and health characteristics for female participants and summarized the mean values of parameters of a complete blood count and chemistry panel conducted during the first trimester and second trimester in pregnant women in JECS, who are regarded as being representative of the general Japanese population [3]
The mean values for white blood cell count (WBC), red blood cell count (RBC), Hb, Ht, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), platelet count (PLT), HbA1c, total cholesterol (T-Cho), low-density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), TG, total protein (TP), and Alb for women in their first trimester in this study fell within these reference ranges [18]
Summary
The Japan Environment and Children’s Study (JECS) is a nationwide birth cohort study launched in January 2011 to evaluate the effects of chemical exposure during the fetal stage and in early childhood on children’s health and development [1]. Based on selected maternal and infant characteristics in the first year of recruitment, the JECS cohort is representative of the general. JECS examines the effects of exposure to a wide range of environmental factors [1]. Previous studies in JECS have reported various profile data on chemical analyses of biospecimens, including the allergic profiles of mothers and fathers [8], metabolic status in. The Japan Environment and Children’s Study (JECS) is a nationwide birth cohort study of environmental factors affecting children’s health and development.
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