Abstract
Ibuprofen is the NSAID most commonly used to treat mild-moderate pain, fever and inflammation in children, although dosage recommendations in infants aged 3–6 months still differ between countries. Based on the available evidence, the short-term use of ibuprofen to manage pain and fever appears to be effective and safe in infants aged 3–6 months who weigh ≥ 5–6 kg. The dosage should be weight-based, with preference given to oral preparations. To minimize the risk of renal toxicity, it is important to ensure than the infant is adequately hydrated.
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