Base‐Promoted Formation of an Annelated Pyrrolo‐1,4‐oxazine Ensemble from 1H‐pyrrol‐2‐ylmethanol and Propargyl Chloride: A Theoretical and Experimental Study

Abstract

AbstractInvited for this month's cover is the group of Prof. Dr. Nadezhda M. Vitkovskaya at Irkutsk State University and the group of Dr. Andrey V. Ivanov at the A. E. Favorsky Irkutsk Institute of Chemistry, Russian Federation. The image shows that three different pyrrole derivatives can be obtained from the same starting reagents. The reaction is easily controlled by the ratio of the reagents, the amount of alkali, and the degree of dilution. The three strings of the balalaika (a Russian folk instrument) that represent these parameters can produce melodies from the same notes symbolizing the reagents. The sheets with quantum‐chemical calculations under the musical notebook symbolize that the experimental work is based on the theoretical investigations. Read the full text of the article at 10.1002/cplu.201900407.