Abstract
Mitochondrial ribosomal RNA (rRNA) of a strain of Saccharomyces cerevisiae differs from cytoplasmic rRNA in sedimentation properties and base composition. Mitochondrial rRNA sediments at 22 S and 15 S, while cytoplasmic rRNA sediments at 26 S and 17 S. Escherichia coli rRNA (23 S, 16 S) was used as the standard of reference. Both components of mitochondrial rRNA have a low guanylic+cytidylic acid content (25–27%). Cytoplasmic rRNA has a considerably higher guanylic+cytidylic acid content (45–48%). The base compositions of mitochondrial and cytoplasmic rRNA's parallel the different base compositions of mitochondrial and nuclear DNA.
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