Abstract

THE test for basal metabolism is accepted as a valuable aid in clinical diagnosis. Although an elevated basal metabolic rate suggests overactivity of the thyroid gland, it is recognized that it may occur in many other clinical states unrelated to the thyroid gland. Interpretation of an increased metabolic rate, therefore, demands careful evaluation of the entire clinical picture. Hyperthyroidism resulting from primary hyperthyroidism (exophthalmic goiter) or adenomatous goiter is the most common cause of an elevated metabolic rate, and the administration of large doses of desiccated thyroid has the same effect. Fear of the metabolic test, neurocirculatory asthenia, various emotional states, and fever frequently cause an increased metabolic rate. Less common causes include dyspnea resulting from heart failure, endocrine diseases such as acromegaly (at times associated with an overactive adenomatous goiter), and Cushing's syndrome, blood diseases such as leukemia and polycythemia, pregnancy, pain, discomfor...

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