Basal E2, FSH, and AFC of Endometrioma Patients Undergoing In Vitro Fertilization (IVF)

Abstract

Background: Endometriosis is a common disease among women of reproductive age and often associated with infertility. Endometrioma is one of the most common manifestations in endometriosis patient. In Vitro Fertilization is one of the methods used as infertility management in endometriosis women. There are some basal parameters that could affect the IVF result, such as basal E2, FSH and AFC. This study aim is to analyze the basal E2, FSH and AFC of women with endometrioma patients compared to non-endometriosis patients. Methods: This is an analytical observational study with case-control method using medical record data at the Fertility Polyclinic of Graha Amerta Dr. Soetomo General Hospital Surabaya, Indonesia in period of 2018-2020. Result: There was a significant difference in basal E2 levels, the group of women with endometrioma had lower basal E2 levels than non-endometriosis. There were no significant differences in basal E2, FSH and AFC in post endometrioma cystectomy group compared to endometrioma with conservative treatment. Conclusion: Endometrioma patients had lower basal E2 level compared to non-endometriosis patient. Consideration of endometrioma cystectomy prior to IVF should be done wisely.