Abstract

Basal cell carcinoma syndrome, also known as Gorlin-Goltz syndrome, is an autosomal-dominant disease characterized by multiple basal cell carcinomas (BCCs) since childhood along with other multiorgan abnormalities. Pigmented and non-pigmented BCC and palmar pits are often small and hardly visible to the naked eye. The main dermatoscopic features of pigmented BCCs are leaf-like and spoke-wheel areas (superficial forms) or blue-gray globules and large ovoid nests (nodular-cystic forms); in non-pigmented BCCs, the presence of branching arborizing vessels is characteristic. Dermatoscopy is also useful for the detection of palmar pits by showing flesh-colored depressed lesions with both blue structure and arborizing vessels or red-dotted vessels.

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